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Lifetime dietary administration of up to nitroglycerin 1058 mg/kg/day of nitroglycerin was not tumorigenic in mice .
Nitroglycerin was mutagenic nitroglycerin in Ames tests performed in 2 different laboratories .
Nevertheless, there was no evidence of mutagenicity nitroglycerin precautions nitroglycerin storage what is nitroglycerin used for nitroglycerin in an in vivo dominant lethal assay with male rats treated with doses up to about 363 mg/kg/day, PO, or in ex vivo cytogenetic tests in rat and dog cells .
In a 3-generation reproduction study, rats received dietary nitroglycerin at doses nitroglycerin up to about 434 mg/kg/day for 6 months prior to mating of the F0 generation, with treatment continuing through successive F1 and F2 generations .
The high dose was associated with decreased feed intake and nitroglycerin body weight gain in both sexes at all matings .
No specific effect on the fertility of the F0 nitroglycerin generation was seen .
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