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After oral administration of NUVIGIL, armodafinil exhibits an apparent monoexponential armodafinil decline from the peak plasma concentration .
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The oral clearance of NUVIGIL is approximately nuvigil mood changes armodafinil package insert waklert vs adderall nuvigil epocrates waklert 33 mL/min .
Drug-Drug armodafinil Interactions The existence of multiple pathways for armodafinil metabolism, as well as the fact that a non CYP-related pathway is the most rapid in metabolizing armodafinil, suggest that there is a low probability of substantive effects on the overall pharmacokinetic profile of NUVIGIL due to CYP inhibition by concomitant medications .
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