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Usage of baclofen:
Safety baclofen and effectiveness in pediatric patients below the age of 12 have not been established .
Clinical studies of baclofen did not include sufficient numbers of subjects baclofen aged 65 and over to determine whether they respond differently from younger subjects .
In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal baclofen function .
Because elderly patients are more likely to have decreased renal function, care should be taken baclofen in dose selection, and it may be useful to monitor renal function .
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