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Usage of zofran:
Ondansetron (Zofran®) Actions/Pharmacology: Blocks the zofran effects of serotonin at 5-HT3-receptor sites (selective antagonist) located in vagal nerve terminals and the chemoreceptor trigger zone in the CNS .
Nausea and vomiting, regardless of mechanism Prior to morphine administration, consider Contraindications: Parkinson’s patients receiving apomorphine Side and Adverse effects: Transient blindness May cause transient dizziness after IV administration May cause prolonged QT interval and/or Torsade de Pointes May cause zofran transient oculogyric crisis and dystonic reactions Adult Administration: 4mg IM or orally dissolving tablet (ODT) 4mg slow IVP over 2 to 5 minutes May repeat any route one time in 10 minutes with SFTP or Base Hospital order Maximum adult dose 8mg Pediatric Administration: Must be 4 years of age and older 4mg slow IVP over 2 to 5 minutes Maximum pediatric dose 4mg .
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