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Precise Incidence Incidence Greater than 1% Precise Incidence Unknown (but less than 1%) (but less than 3%) (but less than 1%) Causal Relationship Probable Causal Relationship Probable Causal Relationship* GASTROINTESTINAL Nausea†, epigastric pain†, heartburn†, diarrhea, abdominal distress, nausea Gastric or duodenal ulcer with and vomiting, indigestion, bleeding and/or perforation, constipation, abdominal cramps or gastrointestinal hemorrhage, melena, Pain, fullness of GI tract (bloating and gastritis, hepatitis, jaundice, abnormal liver function tests; pancreatitis CENTRAL NERVOUS SYSTEM Depression, insomnia, confusion, emotional liability, somnolence, aseptic meningitis with fever and Dizziness†, headache, nervousness coma (see PRECAUTIONS) Precise Incidence Incidence Greater than 1% Precise Incidence Unknown (but less than 1%) (but less than 3%) (but less than 1%) Causal Relationship Probable Causal Relationship Probable Causal Relationship* Vesiculobullous eruptions, urticaria, Rash† (including maculopapular type), erythema multiforme, Stevens- photoallergic skin Johnson syndrome, amount of ibuprofen to take ibuprofen 600 uses ibuprofen 400 mg how many can i take what is the work alopecia Hearing loss, amblyopia (blurred and/or diminished vision, scotomata and/or changes in color vision) (see neuritis, cataracts Precise Incidence Incidence Greater than 1% Precise Incidence Unknown (but less than 1%) (but less than 3%) (but less than 1%) Causal Relationship Probable Causal Relationship Probable Causal Relationship* Neutropenia, agranulocytosis, aplastic anemia, hemolytic anemia (sometimes Coombs positive), thrombocytopenia with or without purpura, eosinophilia, decreases in Bleeding episodes hemoglobin and hematocrit (see METABOLIC/ENDOCRINE Decreased appetite reaction, acidosis Edema, fluid retention (generally responds promptly to drug discontinuation) (see Congestive heart failure in patients Arrhythmias (sinus with marginal cardiac function, tachycardia, sinus elevated blood pressure, palpitations Precise Incidence Incidence Greater than 1% Precise Incidence Unknown (but less than 1%) (but less than 3%) (but less than 1%) Causal Relationship Probable Causal Relationship Probable Causal Relationship* Syndrome of abdominal pain, fever, chills, nausea and vomiting; syndrome .

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