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Usage of methadone:
• Patients should be cautioned that alcohol and other CNS depressants may produce methadone an additive CNS depression when taken with this product and should be avoided .
• Patients should be instructed to seek medical attention immediately if they experience symptoms suggestive of an methadone arrhythmia (such as palpitations, dizziness, lightheadedness, or syncope) when taking Methadose .
• Patients initiating treatment with Methadose should be reassured that the dose of methadone will “hold” for longer periods of time as treatment methadone NDA 17-116/S-021 • Patients should be instructed to keep Methadose in a secure place out of the reach of children and other household members .
Accidental or deliberate ingestion by a child may cause respiratory depression methadone that can result in death .
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