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Oxymorphone (brand names Opana, Numorphan, Numorphone), also known as 14-hydroxydihydromorphinone, is a powerful semi-synthetic opioid analgesic methadone (painkiller) first developed in Germany in 1914, patented in the USA by Endo Pharmaceuticals in 1955 and introduced to the United States market in January 1959 and other .
51 � methadone half life methadone lyrics methadone rise against methadone vs methadose methadone 1 . 43 methadone hours . 6 However, oxymorphone methadone has a significantly longer half life (7-9 hours)7 than does oxycodone, whose mean elimination half-life following a single, oral dose is 3 . Oxycodone is metabolized in part by cytochrome P450 2D6 to methadone oxymorphone, which represents less than 15% of the total administered dose .
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