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Nitrofurantoin Capsules, USP (nitrofurantoin monohydrate/macrocrystals) reaction to macrobid macrobid nausea macrobid prescribing information macrobid pyelonephritis THERAPEUTIC CLASSIFICATION Urinary Tract Antibacterial ACTIONS AND CLINICAL PHARMACOLOGY Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates which inactivate or alter bacterial ribosomal proteins and other macromolecules .
As a result of such inactivations, the vital biochemical processes of protein synthesis, aerobic energy metabolism, DNA synthesis, RNA synthesis, macrobid and cell wall synthesis are inhibited .
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